Kapa Biosystems was founded in 2006 to develop next-generation PCR reagents. Our molecular evolution technology platform is currently being used to optimize enzymes for DNA amplification, next-generation DNA sequencing, and molecular diagnostic applications. The majority of biomedical and research applications were designed around a small subset of native enzymes. The limitations of these applications are often the result of constraints due to enzyme structure or function. Recent advances in molecular evolution have allowed enzymes to be tailored to suit specific application requirements. Enzyme engineering improves existing methods and provides the foundation on which entirely novel applications can be built. Kapa Biosystems conducts advanced protein engineering, taking advantage of recent developments in genomics, proteomics, and synthetic biology.


Main products
	KAPA3G Plant PCR Kits Direct PCR from plant tissue.

	Multiplex PCR : KAPA2G Fast Multiplex PCR Kits

	KAPA HiFi Uracil+ for bisulfite sequencing KAPA HiFi DNA Polymerase provides high fidelity next-generation sequencing library amplification with the highest yield, lowest bias, and most uniform sequence coverage available.

	KAPA Mouse Genotyping Kits -50% on 500 rxns kits. Offer n°02012013-MG-KAPA valid until 30/06/13

	KAPA SYBR® FAST qPCR Kits -50% on KAPA SYBR Fast qPCR Kits. Offer n°20130102-SYBR-KAPA valid until 30/06/2013

	KAPA Taq and Taq HotStart Quality DNA POLYMERASE at low cos t From only 3.5 Cts per Reaction* -20 % on KAPA Taq PolymeraseOffer 05062012-MB valid until 31/12/2012

	KAPA Taq and Taq HotStart Quality DNA POLYMERASE at low cos t From only 3.5 Cts per Reaction* -20 % on KAPA Taq PolymeraseOffer 05062012-MB valid until 30/06/2013

	New NGS Library Preparation Kit KAPA Low TroughPut

	News in Next Genration Sequencing Innovative solution for library preparation

	News in New Genration Sequencing Innovative solution for library preparation

	Molecular Evolution Platform used for Taq polymerase Technology based on site directed mutagenesis of the gene for Taq polymerase and then the selection of the mutated enzyme by its resistance to pressure imposed

	Mix for PCR on difficult templates : KAPA2G Robust PCR Kits Streamline your PCR workflows by consolidating protocols and reaction conditions, increase pass rates, amplify difficult templates without bias, and increase sensitivity – all with a single enzyme. Product list

	Kapa Blood PCR kits Eliminate the need for DNA purification with KAPA Blood PCR kits, containing the first DNA polymerase evolved for whole blood PCR.

	KAPA dNTPs High quality, molecular grade dNTPs.

	High fidelity PCR : KAPA HiFi PCR Kits A second-generation polymerase engineered for extreme fidelity and robustness - 100x fidelity improvement compared to Taq polymerase.

	PCR on long DNA templates : KAPA Long Range PCR Kits Amplify long templates up to 20 kb with extreme sensitivity and increased fidelity.

	KAPA PROBE FAST qPCR Kits KAPA PROBE FAST qPCR Kits have been optimized for versatility and speed – providing fast and reproducible results for genotyping, gene expression analysis, and multiplexing with a single kit.

	KAPA SYBR FAST qPCR Kits KAPA SYBR® FAST qPCR Kits contain a new DNA polymerase specifically designed for qPCR using SYBR ® Green I dye.

	KAPA SYBR® FAST One-Step qRT-PCR Kits KAPA SYBR® FAST One-Step qRT-PCR Kits are designed to perform optimally in stringent qRT-PCR reaction conditions, exhibiting dramatic improvements in sensitivity, specificity, reaction efficiency, and fluorescence.

	KAPA Rapid Ligation System The KAPA Rapid Ligation System is a combination of KAPA Rapid T4 DNA Ligase and an optimized reaction buffer designed to ligate blunt or cohesive end DNA fragments in 5 minutes at room temperature.

	KAPA T4 DNA Ligase KAPA T4 DNA Ligase catalyzes the formation of a phosphodiester bond between 5’ phosphate and 3’ hydroxyl termini in duplex DNA or RNA. This enzyme will join blunt and cohesive end termini as well as repair single stranded nicks in duplex DNA, RNA or DNA/RNA hybrids.

	Routine PCR : KAPA Taq PCR Kits KAPA Taq DNA Polymerase is based on the single-subunit, wild-type Taq DNA polymerase of the thermophilic bacterium Thermus aquaticus. In the HotStart formulation, the enzyme is combined with a proprietary antibody that inactivates the enzyme until the first denaturation step. This eliminates spurious amplification products resulting from non-specific priming events during reaction setup and initiation, and increases overall reaction efficiency and sensitivity.

	HotStart ReadyMix PCR kits

CliniSciences - 183, avenue Georges Clémenceau - 92000 - Nanterre - France
Tel : +33 9 77 40 09 09 - Fax : +33 9 77 40 10 11 - info@clinisciences.com