Catalog Number: 200-52
Mouse Vascular Endothelial Growth Factor-120
Alternate Names: VEGF-A, VPF, glioma-derived endothelial cell mitogen
Vascular Endothelial Growth Factor-A (VEGF-A) was originally isolated from tumor cells and is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability, VEGF-A may play a role in stimulating vasodilatation via nitric oxide-dependent pathways. Mouse VEGF-A has several variants, one being VEGF-120. Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95%. Recombinant mouse VEGF-120 is an alternative spliced version of mouse VEGF-165, consisting of a non-glycosylated homodimer with a molecular weight of 28.2 kDa.
Data Sheet (PDF)