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Rabbit polyclonal antibody to RAG2 (recombination activating gene 2) - TA307957 |
| Imprimer |
 Anti-RAG2 Antibody TrueMAB™ Antibodies - Made against Authentic Protein Antigens 
 Also for RAG2 (NM_000536) | Homo sapiens recombination activating gene 2 (RAG2), transcript variant 1 | | RAG-2 | | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 271 and 519 of RAG2 | | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. | | IgG | | Human | 0.37mg/ml | | Purified by antigen-affinity chromatography. (Protein A or G Sepharose ) | | WB, IHC, IF | WB:1:500-1:3000; IHC:1:100; IF:1:100-1:200; | | This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq] | | |
* Shipping is in business days * OriGene provides validated application data and protocol, with money back guarantee. WB Image Sample (30 ug of whole cell lysate) A: Molt-4 (anti-RAG2 antibody diluted at 1:1000) IHC Image Immunohistochemical analysis of paraffin-embedded DLD1 Xenograft, using RAG2(anti-RAG2 antibody) antibody at 1:100 dilution. IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RAG2(anti-RAG2 antibody) antibody at 1:200 dilution. Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules: - HRP
- Biotin
- PE
- FITC
- DyLight ® 488
- DyLight ® 550
- DyLight ® 594
- DyLight ® 633
* DyLight is a trademark of Thermo-Fisher Scientific Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation. Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support) |
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