Transgenic knock-in mouse : TARGATT™ Kits
Using the TARGATT™ Technology, you can generate your own knockin mouse in 3 months.
Using the novel TARGATT™ system, a gene of interest can be specifically inserted at a well-characterized, transcriptionally-active locus in the mouse genome with guaranteed transgene expression. Tissue-specific and / or ubiquitous expression options are available.Kit components:
- TARGATT™ mRNA
- pBT
- control mRNA
- miTE Buffer
Advantages of TARGATT™ technology:
1. Site-specific gene integration at a transcriptionally-active locus ensures high-level gene expression.
2. Integration happens at an intergenic region; no internal genes are disrupted.
3. The integrase system catalyzes a unidirectional integration event and results in a high efficiency in producing transgenic mice.
4. Gene integration at the same locus allows a precise comparison of the transgenics from one line to another.
