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Globulin is one of the two types of serum proteins, the other being albumin.
The term globulin term encompasses a heterogeneous group of proteins with typical high molecular weight, and both solubility and electrophoretic migration rates lower than for albumin. The normal concentration in blood is 2 to 3.5 g/dl.
It is sometimes used synonymously with globular protein. However, albumin is also a globular protein, but not a globulin. All other serum globular proteins are globulins.
beta 2 Microglobulin
A hormone is a chemical released by one or more cells that affects cells in other parts of the organism.
Most hormones initiate a cellular response by initially combining with either a specific intracellular or cell membrane associated receptor protein. A cell may have several different receptors that recognize the same hormone and activate different signal transduction pathways, or alternatively different hormones and their receptors may invoke the same biochemical pathway.
Inhibin beta A,
An oncoprotein comes from an oncogene, a gene that, when mutated or expressed at high levels, helps turn a normal cell into a tumor cell.
Many abnormal cells normally undergo a programmed form of cellular death.
Activated oncogenes can cause those cells to survive and proliferate instead.
Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer.
ErbB 2 ,
A receptor is a protein molecule, embedded in either the plasma membrane, the cytoplasm of a cell or the nuclear membrane, to which a mobile signaling molecule may attach.
When such binding occurs, the receptor undergoes a conformational change, which ordinarily initiates a cellular response. Ligand-induced changes in receptors result in cellular changes which constitute the biological activity of the ligands.
Estrogen Receptor alpha ,
Estrogen Receptor beta,
alpha Fetoprotein Receptor,
Tumor antigen is a substance produced in tumor cells that triggers an immune response in the host.
Tumor antigens are useful in identifying tumor cells and are potential candidates for use in cancer therapy.
Initially they were broadly classified into two categories based on their pattern of expression: Tumor-Specific Antigens, which are present only on tumor cells and not on any other cell and Tumor-Associated Antigens, which are present on some tumor cells and also some normal cells.
CD5 + CD19,
Carcino Embryonic Antigen CEA,
Lung carcinoma Cluster 2,
MOK protein kinase ,
Melanoma Associated Antigen,
Ovarian Carcinoma-associated Antigen,
Prostate Mucin Antigen,
Prostate Specific Antigen,
alpha 1 Fetoprotein,
15 Lipoxygenase 1,
5 Hydroxyindole acetic acid,
AGR2 + AGR3,
Anterior Gradient 2,
Breast carcinoma amplified sequence 3,
Creatine kinase MT,
EZH 1 + 2,
Epithelial Stromal Interaction 1,
Estrogen-induced gene 121,
Hsp70 + Hsc70,
Retinoblastoma binding protein,
Wilms Tumor Protein,