β-Amyloid (1-15) [183745-81-5]
Référence TP1229-1mg
Conditionnement : 1mg
Marque : TargetMol
β-Amyloid (1-15)
(Synonyms: Amyloid β-Protein (1-15)) Copy Product Info
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.
Cas No. 183745-81-5
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.88%
Appearance:Solid
Color:White
COA HPLC MS
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease. |
| In vitro | Produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP), β-Amyloid (1-15) appears to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition. It may have several advantages compared to measuring longer cerebrospinal fluid (CSF) Aβ species[1]. |
| Synonyms | Amyloid β-Protein (1-15) |
| Molecular Weight | 1826.84 |
| Formula | C78H107N25O27 |
| Cas No. | 183745-81-5 |
| Smiles | [C@H](CC1=CN=CN1)(C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)CCC(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CC(O)=O)=O)CO)=O)=O)=O)CCC(O)=O)=O)[C@H](C)C)=O |
| Relative Density. | 1.59 g/cm3 (Predicted) |
| Sequence | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln |
| Sequence Short | DAEFRHDSGYEVHHQ |
| Storage | Store at low temperature,Keep away from moisture Powder: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | H2O: 30 mg/mL (16.42 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||