β-Melanocyte Stimulating Hormone TFA, human [17908-57-5 ( free case)]

Biological Activity

β-Melanocyte Stimulating Hormone TFA, human is a 22-residue peptide, which acts as an endogenous melanocortin-4 receptor (MC4-R) agonist. β-Melanocyte Stimulating Hormone, human (β-MSH) has high affinity at both human MC4-R transfected into CHO cells (Ki=11.4±0.4 nM) and MC4-R in rat hypothalamic homogenates (Ki=5.0±0.4 nM).

Chemical Information

Molecular Weight	2774.94
Formula	C120H175F3N34O37S
CAS Number	17908-57-5 ( free case)
Solubility (25°C)	Water ≥ 90 mg/mL
Storage	-20°C, protect from light, dry, sealed

References

[1] Chang Cao, et al. Neurosci Lett. The anorexigenic effect of beta-melanocyte-stimulating hormone involves corticotrophin-releasing factor and mesotocin in birds

[2] Diane Nepomuceno, et al. Front Pharmacol. Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro

[3] P C Datta, et al. Neurosci Biobehav Rev. Alpha-melanocyte-stimulating hormone and behavior

[4] G A Bloomfield, et al. Proc R Soc Med. Beta-melanocyte stimulating hormone

[5] No authors listed. Br Med J. Melanocyte-stimulating hormone