Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.

Anti-KLF4 Polyclonal Antibody 2

Imprimer

Conditionnement : 200uL

Demander plus d'informations

Remove All

Copy Product Info

Synonyms:

Catalog No. TMAB-08092 Copy Product Info

Anti-KLF4 Polyclonal Antibody 2 is a Rabbit antibody targeting KLF4. Anti-KLF4 Polyclonal Antibody 2 can be used in WB.

For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity

Description	Anti-KLF4 Polyclonal Antibody 2 is a Rabbit antibody targeting KLF4. Anti-KLF4 Polyclonal Antibody 2 can be used in WB.
Ig Type	IgG
Reactivity	Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse)
Verified Activity	Sample: Lane 1: Mouse Small intestine Lysates Lane 2: Mouse Stomach Lysates Lane 3: Rat Skin Lysates Lane 4: Human A431 cell Lysates Primary: Anti-KLF4 (TMAB-08092) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kDa Observed band size: 56 kDa
Application	WB
Recommended Dose	WB: 1:500-2000
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Nucleus.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1mg/ml
Research Background	KLF4 is a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene. It binds the CACCC core sequence. KLF4 may be involved in the differentiation of epithelial cells and may also function in the development of the skeleton and kidney. KLF4 also has roles as both an oncogene and a tumor suppressor.

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human KLF4
Antigen Species	Human
Gene Name	KLF4
Gene ID	9314
Protein Name	Krueppel-like factor 4
Uniprot ID	O43474
Function	Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Chemical Properties

Molecular Weight	Theoretical: 56 kDa. Actual: 56 kDa.

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
Transport	Shipping with blue ice.

Related Tags: Anti-KLF4 Polyclonal Antibody 2 molecular weight