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> Anti-VEGFB Antibody (9L289)

Anti-VEGFB Antibody (9L289)

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Référence NB-64-163996-25uL

Conditionnement : 25uL

Marque : Neo Biotech


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Anti-VEGFB Antibody (9L289)

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Catalog No. TMAB-14079 Copy Product Info
Anti-VEGFB Antibody (9L289) is a Rabbit antibody targeting VEGFB. Anti-VEGFB Antibody (9L289) can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-VEGFB Antibody (9L289) is a Rabbit antibody targeting VEGFB. Anti-VEGFB Antibody (9L289) can be used in WB.
Ig Type
IgG
Clone
9L289
Reactivity
Human,Mouse
Verified Activity
Western blot analysis of 293T cell transfected with VEGFB recombinant protein. Using VEGFB (TMAB-14079) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
WB
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Tissue SpecificityExpressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundGrowth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Antigen Details
Immunogen
A synthesized peptide: human VEGF B
Antigen Species
Human
Gene Name
VEGFB
Gene ID
7423
Protein Name
Vascular endothelial growth factor B
Uniprot ID
P49765
Function
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs). The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-C and VEGF-D, all of which may exhibit angiogenic function in vivo. VEGF-B, which exists as two alternatively spliced isoforms known as VEGF-B167 and VEGF-B186, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF. VEGF-C binds to and specifically activates Flt-4 and Flk-1.
Chemical Properties
Molecular WeightTheoretical: 22 kDa. Actual: 19 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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