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> Antiviral agent 54

Antiviral agent 54

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Identifiez-vous

Référence HY-161454

Conditionnement : Onrequest

Marque : MedChemExpress


Description

Antiviral agent 54 (compound 33) is a broad-spectrum and orally active antiviral agent. Antiviral agent 54 shows antiviral activity for ZIKV, HCoV-OC43 and influenza A virus (IVA). Antiviral agent 54 decreases the ZIKV RNA and protein level[1].

IC50 & Target

EC50: 0.39 µM (ZIKV); 2.28 µM (HCoV-OC43); 2.69 µM (influenza A)[1]
In Vitro

Antiviral agent 54 (compound 33) (5, 2.5, 1.25, 0.625 µM; 48 h) decreases the ZIKV NS5 protein and RNA level in a dose-dependent manner[1].
Antiviral agent 54 shows antiviral activity for ZIKV, HCoV-OC43 and influenza A virus (IVA) with EC50s of 0.39, 2.28, 2.69 µM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antiviral agent 54 Related Antibodies

Western Blot Analysis[1]

Cell Line: HUVEC cells
Concentration: 5, 2.5, 1.25, 0.625 µM
Incubation Time: 48 h
Result: Decreased the ZIKV NS5 protein level in a dose-dependent manner.

RT-PCR[1]

Cell Line: HUVEC cells
Concentration: 10 µM
Incubation Time: 48 h
Result: Decreased the ZIKV RNA level in a dose-dependent manner.
Masse moléculaire

411.59

Formule

C23H37N7
SMILES

CN(C)CCN(C)CCN(C)C1=CC=NC(CN2CCN(C3=CC=NC=C3)CC2)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références