Ascorbic Acid 6-palmitate

Ascorbic Acid 6-palmitate
Catalog number: B2017574
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 g
Molecular Weight or Concentration: 414.53 g/mol
Supplied as: POWDER
Applications: a molecular tool for various biochemical applications
Storage: RT
Keywords: 6-O-Palmitoyl-L-ascorbic acid, L-Ascorbic acid 6-hexadecanoate, L-Ascorbyl palmitate, Ascorbic acid 6-palmitate, NSC 402451
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV, Walker LC, Wang Y, Levine M. Topical L-ascorbic acid: percutaneous absorption studies Dermatol Surg. 2001 Feb;27(2):137-42.
2: Pinnell SR. Ascorbyl-6-palmitate is not ascorbic acid J Invest Dermatol. 2002 Nov;119(5):991.
3: Li Q, Wu Y, Chen XS, Zeng T, Liu LL, Feng ZQ, Liu DY, Zhu L, Wan LH. Ascorbic_acid_6-palmitate modulates microglia M1/M2 polarization in lipopolysaccharide-stimulated BV-2 cells via PERK/elF2α mediated endoplasmic reticulum stress BMC Complement Med Ther. 2022 Nov 18;22(1):302.
4: Al-Niaimi F, Chiang NYZ. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications J Clin Aesthet Dermatol. 2017 Jul;10(7):14-17. Epub 2017 Jul 1.
5: Mohamed R, Tarannum S, Yariswamy M, Vivek HK, Siddesha JM, Angaswamy N, Vishwanath BS. Ascorbic_acid_6-palmitate: a potent inhibitor of human and soybean lipoxygenase-dependent lipid peroxidation J Pharm Pharmacol. 2014 Jun;66(6):769-78.
6: Nielsen JH, Kristiansen GH, Andersen HJ. Ascorbic_acid and ascorbic_acid_6-palmitate induced oxidation in egg yolk dispersions J Agric Food Chem. 2000 May;48(5):1564-8.
7: Lee KM, Kwon JY, Lee KW, Lee HJ. Ascorbic_acid_6-palmitate suppresses gap-junctional intercellular communication through phosphorylation of connexin 43 via activation of the MEK-ERK pathway Mutat Res. 2009 Jan 15;660(1-2):51-6.
8: Yilmaz O, Ozkan Y, Yildirim M, Oztürk AI, Erşan Y. Effects of alpha lipoic_acid, ascorbic_acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats J Cell Biochem. 2002;86(3):530-9.
9: Kurokawa I, Yoshioka M, Ito S. Split-face comparative clinical trial using glyceryl-octyl-ascorbic_acid/ascorbyl_2-phosphate 6-palmitate/DL-α-tocopherol phosphate complex treatment for postinflammatory hyperpigmentation, postinflammatory erythema and atrophic scar in acne vulgaris J Dermatol. 2019 Oct;46(10):e347-e348.
10: Wang CC, Wu SM. Simultaneous determination of l-ascorbic acid, ascorbic acid-2-phosphate magnesium salt, and ascorbic acid-6-palmitate in commercial cosmetics by micellar electrokinetic capillary electrophoresis Anal Chim Acta. 2006 Aug 18;576(1):124-9.

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