Azaperone [1649-18-9]
Référence HY-B1470-100mg
Conditionnement : 100mg
Marque : MedChemExpress
Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
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Azaperone Chemical Structure
CAS No. : 1649-18-9
This product is a controlled substance and not for sale in your territory.
Description |
Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. |
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Masse moléculaire |
327.40 |
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Formule |
C19H22FN3O |
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CAS No. |
1649-18-9 |
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Appearance |
Solid |
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Color |
Light yellow to yellow |
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SMILES |
O=C(C1=CC=C(F)C=C1)CCCN2CCN(C3=NC=CC=C3)CC2 |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
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Solvant et solubilité |
In Vitro:
DMSO : 50 mg/mL (152.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
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Pureté et documentation |
Purity: 99.68% |
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 3.0544 mL | 15.2718 mL | 30.5437 mL | 76.3592 mL |
5 mM | 0.6109 mL | 3.0544 mL | 6.1087 mL | 15.2718 mL | |
10 mM | 0.3054 mL | 1.5272 mL | 3.0544 mL | 7.6359 mL | |
15 mM | 0.2036 mL | 1.0181 mL | 2.0362 mL | 5.0906 mL | |
20 mM | 0.1527 mL | 0.7636 mL | 1.5272 mL | 3.8180 mL | |
25 mM | 0.1222 mL | 0.6109 mL | 1.2217 mL | 3.0544 mL | |
30 mM | 0.1018 mL | 0.5091 mL | 1.0181 mL | 2.5453 mL | |
40 mM | 0.0764 mL | 0.3818 mL | 0.7636 mL | 1.9090 mL | |
50 mM | 0.0611 mL | 0.3054 mL | 0.6109 mL | 1.5272 mL | |
60 mM | 0.0509 mL | 0.2545 mL | 0.5091 mL | 1.2727 mL | |
80 mM | 0.0382 mL | 0.1909 mL | 0.3818 mL | 0.9545 mL | |
100 mM | 0.0305 mL | 0.1527 mL | 0.3054 mL | 0.7636 mL |