Bassoon antibody
Référence orb152189-100ug
Conditionnement : 100ug
Marque : Biorbyt
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Bassoon antibody
Catalog Number: orb152189
| Catalog Number | orb152189 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to Bassoon (PerCP). Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors.. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | IHC, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein |
| Concentration | 1 mg/ml |
| Dilution range | WB (1:1000), IHC (1:400) |
| Conjugation | PerCP |
| MW | 420kDa |
| Target | Bassoon |
| Entrez | 8927 |
| UniProt ID | Q9UPA5 |
| NCBI | NP_003449.2 |
| Storage | Conjugated antibodies should be stored at 4°C |
| Buffer/Preservatives | PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated |
| Alternative names | BSN antibody, ZNF231 antibody, Neuronal double zin |
| Note | For research use only |
| Application notes | 1 µg/ml of SPC-198 was sufficient for detection of Bassoon in 10 µg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody. |
| Expiration Date | 12 months from date of receipt. |