Beclin1 (Phospho-Ser30) Antibody
Référence MBS9430198-0,1mL
Conditionnement : 0.1mL
Marque : MyBiosource
Beclin1 (Phospho-Ser30) (BECN1) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9430198Background: Beclin-1 participates in the regulation of autophagy and has an important role in development tumorigenesis, and neurodegeneration.Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were… More details
Product Overview
Online Datasheet in PDFProduct Name
Beclin1 (Phospho-Ser30) (BECN1), Polyclonal Antibody
Full Product Name
Beclin1 (Phospho-Ser30) Antibody
Product Gene Name
anti-BECN1 antibody
Product Synonym Names
ATG6; VPS30; beclin1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/mL (lot specific)
Specificity
The antibody detects endogenous level of Beclin1 only when phosphorylated at serine 30.
Preparation and Storage
Store at -20°C.
Applications Tested/Suitable for anti-BECN1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-BECN1 antibody
WB: 1:500 - 1:1000
IHC: 1:50 - 1:100
IP: 1:20 - 1:50
IHC: 1:50 - 1:100
IP: 1:20 - 1:50
Other Notes
Small volumes of anti-BECN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for BECN1 purchase
MBS9430198 is an antibody targeting BECN1. Also known as Beclin1 (Phospho-Ser30) Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for BECN1. It may not necessarily be applicable to this product.
NCBI Official Full Name
beclin-1 isoform a
NCBI Official Synonym Full Names
beclin 1
NCBI Official Symbol
BECN1
NCBI Official Synonym Symbols
ATG6; VPS30; beclin1
UniProt Protein Name
Beclin-1
UniProt Synonym Protein Names
Coiled-coil myosin-like BCL2-interacting protein; Protein GT197
Protein Family
Beclin
UniProt Gene Name
BECN1
UniProt Synonym Gene Names
GT197
NCBI Protein Information
beclin-1
NCBI Summary for BECN1
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Show more UniProt Comments for BECN1
Plays a central role in autophagy (PubMed:23184933, PubMed:28445460). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530, PubMed:26783301). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-BECN1 antibody
| Reference Product | PubMed Publications |
|---|---|
| BCL2L1 antibody | >41 publications with BECN1 and BCL2L1 |
| UVRAG antibody | >30 publications with BECN1 and UVRAG |
| BCL2 antibody | >25 publications with BECN1 and BCL2 |
| ATG14 antibody | >17 publications with BECN1 and ATG14 |
| AMBRA1 antibody | >13 publications with BECN1 and AMBRA1 |
| PIK3C3 antibody | >6 publications with BECN1 and PIK3C3 |
| PIK3R4 antibody | >5 publications with BECN1 and PIK3R4 |
Pathways associated with anti-BECN1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Regulation Of Autophagy Pathway antibodies | Regulation Of Autophagy Pathway Diagram |
| Regulation Of Autophagy Pathway antibodies | Regulation Of Autophagy Pathway Diagram |
| Senescence And Autophagy Pathway antibodies | Senescence And Autophagy Pathway Diagram |
Diseases associated with anti-BECN1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >301 publications with BECN1 and Neoplasms |
| Nervous System Diseases Antibodies | >78 publications with BECN1 and Nervous System Diseases |
| Breast Neoplasms Antibodies | >50 publications with BECN1 and Breast Neoplasms |
| Necrosis Antibodies | >42 publications with BECN1 and Necrosis |
| Liver Diseases Antibodies | >37 publications with BECN1 and Liver Diseases |
| Cardiovascular Diseases Antibodies | >33 publications with BECN1 and Cardiovascular Diseases |
| Drug Toxicity Antibodies | >31 publications with BECN1 and Drug Toxicity |
| Carcinoma, Hepatocellular Antibodies | >31 publications with BECN1 and Carcinoma, Hepatocellular |
| Inflammation Antibodies | >25 publications with BECN1 and Inflammation |
| Ovarian Neoplasms Antibodies | >21 publications with BECN1 and Ovarian Neoplasms |
Organs/Tissues associated with anti-BECN1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >66 publications with BECN1 and Brain |
| Liver Antibodies | >51 publications with BECN1 and Liver |
| Blood Antibodies | >41 publications with BECN1 and Blood |
| Muscle Antibodies | >32 publications with BECN1 and Muscle |
| Lung Antibodies | >28 publications with BECN1 and Lung |
| Heart Antibodies | >27 publications with BECN1 and Heart |
| Vascular Antibodies | >23 publications with BECN1 and Vascular |
| Nerve Antibodies | >23 publications with BECN1 and Nerve |
| Prostate Antibodies | >20 publications with BECN1 and Prostate |
| Lymph Antibodies | >19 publications with BECN1 and Lymph |


