Beta-(1,3)-D-Glucan [9012-72-0]

Biological Activity

D-Glucan (Beta-Glucan) is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK.

Chemical Information

CAS Number	9012-72-0
Form	Powder
Solubility (25°C)	DMSO 60 mg/mL Water 20 mg/mL (Use as a suspension)
Storage	Powder          -20°C   3 years ;  4°C   2 years In solvent       -80°C   6 months ;  -20°C   1 month

References

[1] Robert Pylkknen, et al. Nanoscale. β-1,3-Glucan synthesis, novel supramolecular self-assembly, characterization and application

[2] Gregory S Bulmer, et al. Carbohydr Res. Recent advances in enzymatic synthesis of β-glucan and cellulose

[3] Lijuan Wu, et al. Int J Biol Macromol. Antitumor effect of soluble β-glucan as an immune stimulant

[4] Johannes Wagener, et al. Curr Top Microbiol Immunol. α- and β-1,3-Glucan Synthesis and Remodeling

[5] Eiji Suzuki, et al. Cell Mol Life Sci. Distribution of glucan-branching enzymes among prokaryotes