Overview
Hormonally active metabolite of vitamin D
Chemical Properties
| Molecular Formula | C27H44O3 |
| Molecular Weight | 416.6 |
| CAS Numbers | 32222-06-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 9,10-secocholesta-5Z,7E,10(19)-triene-1α,3β,25-triol |
| InChl Key | GMRQFYUYWCNGIN-NKMMMXOESA-N |
| InChl Code | InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1 |
| SMILES Code | O[C@@H](C[C@H](O)C/1=C)CC1=CC=C2[C@@](CC[C@@]3([C@H](C)CCCC(C)(O)C)00)(00)[C@]3(C)CCC2 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
1α,25-dihydroxy Vitamin D3; Rocaltrol; Calcijex; Topitriol; Silkis; Soltriol;
References
1) Kumar, R. Metabolism of 1,25-dihydroxyvitamin D3. Physiol. Rev. 64(2), 478-505 (1984).
2) Bikle, D.D., Gee, E., Halloran, B., et al. Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. J. Clin. Invest. 74(6), 1966-1971 (1984).