CD68 antibody [KP1]
Référence GTX73643-1ml
Conditionnement : 1ml
Marque : Genetex
Host | Mouse |
---|---|
Clonality | Monoclonal |
Clone Name | KP1 |
Isotype | IgG1 |
Application | IHC-P |
Reactivity | Human |
Package | 1 ml |
View product citations for antibody GTX73643 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
IHC-P | 1:50-1:100 |
Note : IHC-PRecommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins. |
Not tested in other applications.
Calculated MW
37 kDa. ( Note )
Product Note
This antibody is specific to macrophages in a wide variety of human tissues. It reacts with myeloid precursors and peripheral blood granulocytes. It also stains a cell population known as plasmacytoid T cells.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Subcellular fraction of human alveolar macrophages.
Purification
Purified IgG
Conjugation
Unconjugated
RRID
AB_375045
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD68 molecule , GP110 , LAMP4 , SCARD1
Background
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Database
DATA IMAGES
GTX73643 IHC-P ImageIHC-P analysis of human tonsil tissue using GTX73643 CD68 antibody [KP1]. |
Clone Reference
Wu Y et al. Ann Transl Med 2022; 10 (10):569 Lipid-lowering treatment in a rabbit model of atherosclerosis: a vessel wall magnetic resonance imaging study.
REVIEW
Clone Reference
Wu Y et al. Ann Transl Med 2022; 10 (10):569 Lipid-lowering treatment in a rabbit model of atherosclerosis: a vessel wall magnetic resonance imaging study.
SDS | |
---|---|
PBS.pdf | |
Sodium Azide.pdf |
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Référence
Description
Cond.
Prix HT