CHIR98014 HCl (252935-94-7 free base)
Référence T3074L-100mg
Conditionnement : 100mg
Marque : TargetMol
CHIR98014 HCl (252935-94-7 free base) (Synonyms: CT-98014, CHIR-98014 hydrochloride, CHIR98014 HCl, CHIR-9801...)
CHIR98014 HCl (252935-94-7 free base)
Copy Product InfoSynonyms CT-98014, CHIR-98014 hydrochloride, CHIR98014 HCl, CHIR-98014, CHIR98014, CHIR 98014
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | CHIR98014 is a reversible, cell-permeable inhibitor of GSK3α and GSK3β (IC50s: 0.65 and 0.58 nM). Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50: 106 nM), potentiates insulin-dependent glucose transport in isolated muscle strips, and improves glucose disposal in diabetic animals. |
| Synonyms | CT-98014, CHIR-98014 hydrochloride, CHIR98014 HCl, CHIR-98014, CHIR98014, CHIR 98014 |
| Molecular Weight | 559.23 |
| Formula | C20H19Cl4N9O2 |
| Smiles | NC1=NC(NCCNC2=NC=C(N3C=CN=C3)C(C4=CC=C(Cl)C=C4Cl)=N2)=CC=C1[N+]([O-])=O.09Cl.09Cl |
| Relative Density. | no data available |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |