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> FGF-7/KGF Protein, Mouse, Recombinant

FGF-7/KGF Protein, Mouse, Recombinant

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Référence NB-64-128277-5ug

Conditionnement : 5ug

Marque : Neo Biotech


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FGF-7/KGF Protein, Mouse, Recombinant

(Synonyms: Keratinocyte Growth Factor, HBGF-7, Fibroblast Growth Factor-7, FGF7) Copy Product Info

Synonyms: Keratinocyte Growth Factor, HBGF-7, Fibroblast Growth Factor-7, FGF7

Catalog No. TMPS-00172 Copy Product Info
FGF-7/KGF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P36363.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 97% as analyzed by SDS-PAGE，> 97% as analyzed by HPLC
Appearance:Lyophilized powder
Color:White
Contact us for more batch information

Product Information

Bioactivity
Bioactivity
ED 50 < 2.0 ng/ml, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 5.0 × 10 5 units/mg.
Description
FGF-7/KGF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P36363.
Species
Mouse
Expression System
E. coli
TagTag Free
Accession NumberP36363
ConstructionCys32-Thr194
Protein Purity
> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin< 0.2 EU/μg of protein as determined by the LAL method.
FormulationLyophilized from a 0.2 μm filtered solution in PBS.
ReconstitutionIt is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in PBS up to 100 μg/ml.
SynonymsKeratinocyte Growth Factor, HBGF-7, Fibroblast Growth Factor-7, FGF7
Research Background
Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF’s roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands., KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney.
Chemical Properties
Molecular Weight~18.7 kDa (Reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageUpon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

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Related Tags: FGF-7/KGF Protein, Mouse, Recombinant chemical structure | FGF-7/KGF Protein, Mouse, Recombinant molecular weight