FGF17 Antibody

Référence MBS8582058-0,1mL-Biotin

Conditionnement : 0.1mL(Biotin)

Marque : MyBiosource


FGF17 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582058

MBS8582058 is an antibody targeting FGF17. Also known as FGF17 Antibody. Reactive in Human, Mouse, Rat, Bovine, Dog, Pig, Monkey, Sheep. Host: Rabbit. Rabbit polyclonal antibody to FGF17 More details

Product Overview

Online Datasheet in PDF
Product Name
FGF17, Polyclonal Antibody
Full Product Name
FGF17 Antibody
Product Gene Name
anti-FGF17 antibody
Product Synonym Names
Fibroblast growth factor 17; FGF-17
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Dog, Pig, Monkey, Sheep
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of FGF17 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
OMIM
603725
3D Structure
ModBase 3D Structure for O60258
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human FGF17. The exact sequence is proprietary.

Product Categories/Family for anti-FGF17 antibody

Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FGF17 antibody
Western Blot (WB)
Application Notes for anti-FGF17 antibody
WB: 1:500-1:1000

Other Notes

Small volumes of anti-FGF17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF17. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibroblast growth factor 17 isoform 1
NCBI Official Synonym Full Names
fibroblast growth factor 17
NCBI Official Symbol
FGF17
NCBI Official Synonym Symbols
HH20; FGF-13; FGF-17
UniProt Protein Name
Fibroblast growth factor 17
Protein Family
Fibroblast growth factor
UniProt Gene Name
FGF17
UniProt Synonym Gene Names
FGF-17
UniProt Entry Name
FGF17_HUMAN
NCBI Protein Information
fibroblast growth factor 17

NCBI Summary for FGF17

This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
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UniProt Comments for FGF17

FGF17: Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development. Belongs to the heparin-binding growth factors family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; type 2 fibroblast growth factor receptor binding; type 1 fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; nervous system development; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; cell-cell signaling; positive regulation of cell proliferation; insulin receptor signaling pathway; innate immune response; signal transduction

Disease: Hypogonadotropic Hypogonadism 20 With Or Without Anosmia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FGF17 antibody

 Reference Product  PubMed Publications
 FGFR1 antibody  >10 publications with FGF17 and FGFR1
 SHH antibody  >6 publications with FGF17 and SHH
 FGFR2 antibody  >6 publications with FGF17 and FGFR2
 FGFR3 antibody  >5 publications with FGF17 and FGFR3
 FGFR4 antibody  >3 publications with FGF17 and FGFR4
 MET antibody  >2 publications with FGF17 and MET

Pathways associated with anti-FGF17 antibody

 Products by Pathway  Pathway Diagram
 Activated Point Mutants Of FGFR2 Pathway antibodies  Activated Point Mutants Of FGFR2 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGFR Ligand Binding And Activation Pathway antibodies  FGFR Ligand Binding And Activation Pathway Diagram

Diseases associated with anti-FGF17 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with FGF17 and Nervous System Diseases
 Brain Diseases Antibodies  >4 publications with FGF17 and Brain Diseases
 Hyperplasia Antibodies  >2 publications with FGF17 and Hyperplasia
 Learning Disorders Antibodies  >2 publications with FGF17 and Learning Disorders
 Skin Abnormalities Antibodies  >1 publications with FGF17 and Skin Abnormalities
 Breast Neoplasms Antibodies  >1 publications with FGF17 and Breast Neoplasms
 Movement Disorders Antibodies  >1 publications with FGF17 and Movement Disorders
 Seizures Antibodies  >1 publications with FGF17 and Seizures
 Abnormalities, Multiple Antibodies  >1 publications with FGF17 and Abnormalities, Multiple
 Skin Diseases Antibodies  >1 publications with FGF17 and Skin Diseases

Organs/Tissues associated with anti-FGF17 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >31 publications with FGF17 and Brain
 Embryonic Tissue Antibodies  >15 publications with FGF17 and Embryonic Tissue