Glycochenodeoxycholic acid [640-79-9]

Biological Activity

Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. 

Chemical Information

Molecular Weight	449.62
Formula	C26H43NO5
CAS Number	640-79-9
Solubility (25°C)	DMSO 72 mg/mL
Storage	2-8°C, dry, sealed

References

[1] Jieli Lu, et al. Association of Serum Bile Acids Profile and Pathway Dysregulation With the Risk of Developing Diabetes Among Normoglycemic Chinese Adults: Findings From the 4C Study

[2] Changying Shi, et al. Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells

[3] Weifeng Lan, et al. Glycochenodeoxycholic acid impairs transcription factor E3 -dependent autophagy-lysosome machinery by disrupting reactive oxygen species homeostasis in L02 cells

[4] Lulu Sun, et al. Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters

[5] S M Qiu, et al. Glycochenodeoxycholic acid inhibits calcium phosphate precipitation in vitro by preventing the transformation of amorphous calcium phosphate to calcium hydroxyapatite