IL2 Receptor alpha antibody [BC96] (PE)
Cat. No. GTX01471-08
Cat. No. GTX01471-08
![Anti-IL2 Receptor alpha antibody [BC96] (PE) used in Flow cytometry (FCM). GTX01471-08](/proxy_img/aHR0cDovL3d3dy5nZW5ldGV4LmNvbS91cGxvYWQvd2Vic2l0ZS9wcm91Y3RfaW1nL21pZGRsZS9HVFgwMTQ3MS0wOC9HVFgwMTQ3MS0wOF8yMDIwMDQyOF9GQUNTMTAzX3dfMjMwNTMxMjFfMTYzLndlYnA=.webp)
GTX01471-08 FCM Image
FACS analysis of human peripheral blood lymphocytes using GTX01471-08 IL2 Receptor alpha antibody [BC96] (PE).
Right panel : primary antibody
Left panel : isotype control
antibody amount : 0.06 μg (5 μl)
This IL2 Receptor alpha antibody [BC96] (PE) (GTX01471-08) is a mouse monoclonal antibody validated for detection of IL2 Receptor alpha by FCM. Reactive to human, baboon, chimpanzee, and other species.
Summary
The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells. The BC96 antibody may be used as a marker for expression of CD25 during T and B cell development, on activated mature T and B cells, and for its expression at high levels on natural T regulatory cells (nTreg cells) in the thymus or periphery, and on ?nduced??peripheral Tregs.