Kell blood group glycoprotein

Référence MBS7042979-0,02mg

Conditionnement : 0.02mg

Marque : MyBiosource


Kell Blood Group Glycoprotein (KEL) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7042979

This is a recombinant transmembrane protein expressed in a cell-free expression system. More details

Product Overview

Online Datasheet in PDF
Product Name
Kell blood group glycoprotein, Recombinant Protein
Full Product Name
Kell blood group glycoprotein
Product Gene Name
KEL recombinant protein
Sequence
MEGGDQSEEE PRERSQAGGM GTLWSQESTP EERLPVEGSR PWAVARRVLT AILILGLLLC FSVLLFYNFQ NCGPRPCETS VCLDLRDHYL ASGNTSVAPC TDFFSFACGR AKETNNSFQE LATKNKNRLR RILEVQNSWH PGSGEEKAFQ FYNSCMDTLA IEAAGTGPLR QVIEELGGWR ISGKWTSLNF NRTLRLLMSQ YGHFPFFRAY LGPHPASPHT PVIQIDQPEF DVPLKQDQEQ KIYAQIFREY LTYLNQLGTL LGGDPSKVQE HSSLSISITS RLFQFLRPLE QRRAQGKLFQ MVTIDQLKEM APAIDWLSCL QATFTPMSLS PSQSLVVHDV EYLKNMSQLV EEMLLKQRDF LQSHMILGLV VTLSPALDSQ FQEARRKLSQ KLRELTEQPP MPARPRWMKC VEETGTFFEP TLAALFVREA FGPSTRSAAM KLFTAIRDAL ITRLRNLPWM NEETQNMAQD KVAQLQVEMG ASEWALKPEL ARQEYNDIQL GSSFLQSVLS CVRSLRARIV QSFLQPHPQH RWKVSPWDVN AYYSVSDHVV VFPAGLLQPP FFHPGYPRAV NFGAAGSIMA HELLHIFYQL LLPGGCLACD NHALQEAHLC LKRHYAAFPL PSRTSFNDSL TFLENAADVG GLAIALQAYS KRLLRHHGET VLPSLDLSPQ QIFFRSYAQV MCRKPSPQDS HDTHSPPHLR VHGPLSSTPA FARYFRCARG ALLNPSSRCQ LW
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Molecular Weight
82,824 Da
Sequence Positions
1-732aa; full length protein
OMIM
110900
3D Structure
ModBase 3D Structure for P23276
Species
Homo sapiens (Human)

Product Categories/Family for KEL recombinant protein

Transmembrane Protein
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KEL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KEL purchase

MBS7042979 is a recombinant protein targeting KEL. Also known as Kell blood group glycoprotein. Host: Cell Free Expression.

Additional Details

NCBI/Uniprot data below describe general gene information for KEL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kell blood group glycoprotein
NCBI Official Synonym Full Names
Kell blood group, metallo-endopeptidase
NCBI Official Symbol
KEL
NCBI Official Synonym Symbols
ECE3; CD238
UniProt Protein Name
Kell blood group glycoprotein
UniProt Synonym Protein Names
CD_antigen: CD238
Protein Family
Kell blood group glycoprotein
UniProt Gene Name
KEL
UniProt Entry Name
KELL_HUMAN
NCBI Protein Information
kell blood group glycoprotein

NCBI Summary for KEL

This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]
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UniProt Comments for KEL

KEL: Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. Belongs to the peptidase M13 family.

Protein type: EC 3.4.24.-; Protease; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: integral to membrane; plasma membrane

Molecular Function: metalloendopeptidase activity; protein binding

Biological Process: vasoconstriction

Disease: Blood Group--kell System
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KEL recombinant protein

 Reference Product  PubMed Publications
 RHCE recombinant protein  >16 publications with KEL and RHCE
 PIP recombinant protein  >6 publications with KEL and PIP
 ITGA2 recombinant protein  >1 publications with KEL and ITGA2

Pathways associated with KEL recombinant protein

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with KEL recombinant protein

 Disease Name  Pubmed Publications
 Male Urogenital Diseases Antibodies  >22 publications with KEL and Male Urogenital Diseases
 Kidney Diseases Antibodies  >21 publications with KEL and Kidney Diseases
 Anemia Antibodies  >18 publications with KEL and Anemia
 Lung Diseases Antibodies  >17 publications with KEL and Lung Diseases
 Liver Diseases Antibodies  >15 publications with KEL and Liver Diseases
 Disease Models, Animal Antibodies  >14 publications with KEL and Disease Models, Animal
 Neurologic Manifestations Antibodies  >13 publications with KEL and Neurologic Manifestations
 Inflammation Antibodies  >10 publications with KEL and Inflammation
 Hypertension Antibodies  >8 publications with KEL and Hypertension
 Poisoning Antibodies  >6 publications with KEL and Poisoning

Organs/Tissues associated with KEL recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >25 publications with KEL and Brain
 Lung Antibodies  >14 publications with KEL and Lung
 Skin Antibodies  >14 publications with KEL and Skin
 Spleen Antibodies  >10 publications with KEL and Spleen
 Bone Marrow Antibodies  >8 publications with KEL and Bone Marrow
 Ovary Antibodies  >7 publications with KEL and Ovary
 Testis Antibodies  >5 publications with KEL and Testis
 Embryonic Tissue Antibodies  >4 publications with KEL and Embryonic Tissue
 Placenta Antibodies  >2 publications with KEL and Placenta
 Uncharacterized Tissue Antibodies  >1 publications with KEL and Uncharacterized Tissue