KLF4 Recombinant Protein
Référence OPCD04684-10UG
Conditionnement : 10ug
Marque : Aviva Systems Biology
KLF4 Recombinant Protein (OPCD04684)
| Datasheets/Manuals | Printable datasheet for KLF4 Recombinant Protein (OPCD04684) |
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| Predicted Species Reactivity | Mouse|Mus musculus |
|---|---|
| Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
| Host | E.coli |
| Conjugation | Unconjugated |
| Application | Ctrl (+), SDS-PAGE, WB |
| Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
| :: | Residues: Ser240-His478 |
| :: | Subcellular Location: Nucleus |
| Reconstitution and Storage | 2°C to 8°C|-80°C |
| Concentration | 200 ug/mL (prior to lyoph) |
| Purity | > 95% |
| Source | E.coli |
| Tag | N-terminal His Tag |
| Gene Symbol | Klf4 |
|---|---|
| Gene Full Name | Kruppel-like factor 4 (gut) |
| Alias Symbols | epithelial zinc finger protein EZF;EZF;Gkl;Gklf;gut-enriched krueppel-like factor;Krueppel-like factor 4;Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF);kruppel-like factor 4 isoform Klf4-108;kruppel-like factor 4 isoform Klf4-1355;kruppel-like factor 4 isoform Klf4-1482;kruppel-like factor 4 isoform Klf4-178;kruppel-like factor 4 isoform Klf4-343;kruppel-like factor 4 isoform Klf4-375;kruppel-like factor 4 isoform Klf4-51;kruppel-like factor 4 isoform Klf4-550;kruppel-like factor 4 isoform Klf4-725;Zi;Zie. |
| NCBI Gene Id | 16600 |
| Protein Name | Krueppel-like factor 4 |
| Description of Target | Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity). |
| Uniprot ID | Q60793 |
| Protein Accession # | NP_034767.2 |
| Nucleotide Accession # | NM_010637.3 |
| Protein Size (# AA) | Ser240~His478 |
| Molecular Weight | 33kDa |
