KYNU Antibody - C-terminal region - HRP
Référence ARP46037_P050-HRP
Conditionnement : 100ul
Marque : Aviva Systems Biology
KYNU Antibody - C-terminal region : HRP (ARP46037_P050-HRP)
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| Datasheets/Manuals | Printable datasheet for anti-KYNU (ARP46037_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | IHC, WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human KYNU |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%; Yeast: 93% |
| Peptide Sequence | Synthetic peptide located within the following region: LAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-KYNU (ARP46037_P050-HRP) antibody is Catalog # AAP46037 (Previous Catalog # AAPS16912) |
| Sample Type Confirmation | KYNU is supported by BioGPS gene expression data to be expressed in HepG2 |
| Reference | Suzuki,Y., Gene 200 (1-2), 149-156 (1997) |
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| Gene Symbol | KYNU |
| Gene Full Name | Kynureninase |
| Alias Symbols | KYNUU, VCRL2 |
| NCBI Gene Id | 8942 |
| Protein Name | Kynureninase |
| Description of Target | Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q16719 |
| Protein Accession # | NP_003928 |
| Nucleotide Accession # | NM_003937 |
| Protein Size (# AA) | 465 |
| Molecular Weight | 52kDa |
| Protein Interactions | LDHAL6B; BCCIP; CNDP2; NAGK; CHORDC1; C11orf58; NDRG1; GDA; SMS; RPS6KA1; PEPD; MVD; LDHA; GSR; GNS; CSE1L; ADSS; LYN; UBC; PALM2; SMEK2; SSU72; SIRT1; NUP210; SEC23IP; COIL; TPM3; SMARCD2; SGTA; PPM1G; ASNS; |
