Mouse Adam17 activation kit by CRISPRa

Référence GA200063

Conditionnement : 1kit


Mouse Adam17 activation kit by CRISPRa

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SKU
GA200063
Adam17 CRISPRa kit - CRISPR gene activation of mouse a disintegrin and metallopeptidase domain 17
 
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Adam17
Locus ID 11491
Components

GA200063G1, Adam17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200063G2, Adam17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200063G3, Adam17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001277266, NM_001291871, NM_009615, NR_102380, NR_120376
UniProt ID Q9Z0F8
Synonyms CD156b; Tace
Summary This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that is involved in the proteolytic release of membrane-bound proteins in a process called ectodomain shedding. Mice lacking the encoded protein die in utero or fail to survive beyond one week of age. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. provided by RefSeq, May 2016
SKU Description Size
KN500818 Adam17 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit

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