Perforin Antibody - PerCP Conjugated
Référence OADB00420
Conditionnement : 1mL
Marque : Aviva Systems Biology
Perforin Antibody - PerCP Conjugated (OADB00420)
| Datasheets/Manuals | Printable datasheet for anti-Perforin (OADB00420) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Lyophilized |
| Clonality | Monoclonal |
| Clone | B-D48 |
| Isotype | Mouse IgG1 |
| Host | Mouse |
| Conjugation | PERCP: Peridinin Chlorophyll Protein Complex |
| Application | FC |
| Reconstitution and Storage | Stable at +2-8C for 12 months. DO NOT FREEZE |
| Purification | Ion exchange chromatography |
| Concentration | 100 tests/1mL |
| Preservative | Sodium Azide |
| Specificity | Recognizes human Perforin, a 70 kDa protein |
| Formulation | Phosphate-buffered saline with 5% BSA and 0.1% sodium azide |
| Storage Buffer | Phosphate-buffered saline with 5% BSA and 0.1% sodium azide |
| Gene Symbol | Perforin |
|---|---|
| Gene Full Name | perforin 1 |
| Alias Symbols | P1, PFP, HPLH2 |
| NCBI Gene Id | 5551 |
| Protein Name | perforin-1 |
| Description of Target | The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. |
| Uniprot ID | P14222 |
| Protein Accession # | NP_001076585.1 |
| Nucleotide Accession # | NM_001083116.1 |
| Molecular Weight | 61 kDa |
