PG 9 (maleate) [155649-00-6]

PG 9 maleate is a compound with analgesic and anti-memory loss activity. PG 9 maleate exerts analgesic effects by enhancing central cholinergic transmission. PG 9 maleate protects against memory loss caused by scopolamine or dicyclomine within a specific dose range. The affinity profile of PG 9 maleate indicates significant selectivity among the M4/M1 receptor subtypes, which may be the mechanism for its analgesic and anti-memory loss effects. PG 9 maleate can increase the release of acetylcholine, thereby improving its biological activity^[1].

468.34

C₂₁H₂₆BrNO₆

155649-00-6

O=C(C(C1=CC=C(Br)C=C1)C)O[C@H]2C[C@H]3CC[C@H](N3C)C2.O=C(O)/C=C\C(O)=O

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• [1]. Antinociceptive and antiamnesic properties of the presynaptic cholinergic amplifier PG-9  [Content Brief]