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Prostaglandin E1 [745-65-3]

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Référence NB-64-07339-5mg

Conditionnement : 5mg

Marque : Neo Biotech

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Prostaglandin E1 (Synonyms: PGE1, Alprostadil)

Catalog No. T1626 Copy Product Info

Purity: 99.93%

Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP.

Prostaglandin E1

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Synonyms PGE1, Alprostadil

Cas No. 745-65-3

Batch Information

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Purity:99.93%

Appearance:Solid

Color:White

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description

Synonyms

PGE1, Alprostadil

Chemical Properties

Molecular Weight	354.48
Formula	C₂₀H₃₄O₅
Cas No.	745-65-3
Smiles	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
Relative Density.	1.0458 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (282.1 mM)

H2O: <1 mg/mL (insoluble)

Ethanol: 100 mg/mL (282.1 mM)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3 mg/mL (8.46 mM)

10% DMSO+90% PBS: 3 mg/mL (8.46 mM)

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.8210 mL	14.1052 mL	28.2103 mL	141.0517 mL
5 mM	0.5642 mL	2.8210 mL	5.6421 mL	28.2103 mL
10 mM	0.2821 mL	1.4105 mL	2.8210 mL	14.1052 mL
20 mM	0.1411 mL	0.7053 mL	1.4105 mL	7.0526 mL
50 mM	0.0564 mL	0.2821 mL	0.5642 mL	2.8210 mL
100 mM	0.0282 mL	0.1411 mL	0.2821 mL	1.4105 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.