PTPRC Antibody
Référence OAEE00880
Conditionnement : 0.1mg(C100)
Marque : Aviva Systems Biology
| Datasheets/Manuals | Printable datasheet for PTPRC Antibody |
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| Predicted Species Reactivity | Cat|Human|Mouse |
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| Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | RA3-6B2 |
| Isotype | IgG2a |
| Host | Rat |
| Conjugation | APC |
| Application | FC |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Abelson murine leukemia virus-induced pre-B tumor cells |
| Purification | Purified by size-exclusion chromatography |
| Concentration | 0.5 mg/ml |
| Specificity | The rat monoclonal antibody RA3-6B2 recognizes an epitope on CD45R, which is expressed at all developmental stages of B cells, including activated B cells, but also on subsets of NK and T cells. T cells detected by this antibody are supposed to be in activated state. |
| Formulation | APC |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Reference | Cappione AJ, Pugh-Bernard AE, Anolik JH, Sanz I: Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytes. J Immunol. 2004 Apr 1;172(7):4298-307. Montecino-Rodriguez E, Leathers H, Dorshkind K: Identification of a B-1 B cell-specified progenitor. Nat Immunol. 2006 Mar;7(3):293-301. Rothaeusler K, Baumgarth N: Evaluation of intranuclear BrdU detection procedures for use in multicolor flow cytometry. Cytometry A. 2006 Apr;69(4):249-59. Rada C, Ehrenstein MR, Neuberger MS, Milstein C: Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting. Immunity. 1998 Jul;9(1):135-41. Tsurui H, Nishimura H, Hattori S, Hirose S, Okumura K, Shirai T: Seven-color fluorescence imaging of tissue samples based on Fourier spectroscopy and singular value decomposition. J Histochem Cytochem. 2000 May;48(5):653-62. Watanabe Y, Akaike T: Activation signal induces the expression of B cell-specific CD45R epitope (6B2) on murine T cells. Scand J Immunol. 1994 May;39(5):419-25. |
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| Gene Symbol | PTPRC |
| Gene Full Name | Receptor-type tyrosine-protein phosphatase C |
| Alias Symbols | LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180 |
| NCBI Gene Id | 5788 |
| Protein Name | Receptor-type tyrosine-protein phosphatase C |
| Uniprot ID | P08575 |
| Protein Accession # | NP_002829.3; NP_563578.2 |
| Nucleotide Accession # | NM_002838.4; NM_080921.3 |
