Rat Guanidinoacetate-N-Methyltransferase (GAMT) Antibody Pair Kit (with Standard)

Référence MBS2101730-10x96

Conditionnement : 10x96Tests

Marque : MyBiosource


Guanidinoacetate-N-Methyltransferase (GAMT) Antibody Pair Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2101730
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MBS2101730 is an antibody pair kit targeting GAMT. Also known as Rat Guanidinoacetate-N-Methyltransferase (GAMT) Antibody Pair Kit (with Standard). Reactive in Rat. More details

Product Overview

Product Name
Guanidinoacetate-N-Methyltransferase (GAMT), Antibody Pair Kit
Full Product Name
Rat Guanidinoacetate-N-Methyltransferase (GAMT) Antibody Pair Kit (with Standard)
Product Gene Name
GAMT antibody pair kit
Product Synonym Names
PIG2; TP53I2; Guanidinoacetate Methyltransferase; Guanidinoacetate Transmethylase; Methionine-Guanidinoacetic Transmethylase; Guanidoacetate Methyltransferase
Species Reactivity
Rat
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
31.2-2000ng/mL
Molecular Weight
29,377 Da
OMIM
Z49878 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Standard
Recombinant GAMT (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Product Categories/Family for GAMT antibody pair kit

ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for GAMT antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex

Other Notes

Small volumes of GAMT antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GAMT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
guanidinoacetate N-methyltransferase
NCBI Official Synonym Full Names
guanidinoacetate N-methyltransferase
NCBI Official Symbol
GAMT
NCBI Official Synonym Symbols
PIG2; CCDS2; TP53I2; HEL-S-20
UniProt Protein Name
Guanidinoacetate N-methyltransferase
Protein Family
Guanidinoacetate N-methyltransferase
UniProt Gene Name
GAMT
NCBI Protein Information
guanidinoacetate N-methyltransferase

NCBI Summary for GAMT

The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13. [provided by RefSeq, Feb 2012]
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UniProt Comments for GAMT

Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor (PubMed:26003046, PubMed:24415674, PubMed:26319512). Important in nervous system development (PubMed:24415674).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GAMT antibody pair kit

 Reference Product  PubMed Publications
 GATM antibody pair kit  >4 publications with GAMT and GATM
 CKB antibody pair kit  >1 publications with GAMT and CKB

Pathways associated with GAMT antibody pair kit

 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Creatine Metabolism Pathway antibodies  Creatine Metabolism Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram

Diseases associated with GAMT antibody pair kit

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >53 publications with GAMT and Nervous System Diseases
 Brain Diseases Antibodies  >42 publications with GAMT and Brain Diseases
 Guanidinoacetate methyltransferase deficiency Antibodies  >34 publications with GAMT and Guanidinoacetate methyltransferase deficiency
 Seizures Antibodies  >23 publications with GAMT and Seizures
 Intellectual Disability Antibodies  >21 publications with GAMT and Intellectual Disability
 Amino Acid Metabolism, Inborn Errors Antibodies  >17 publications with GAMT and Amino Acid Metabolism, Inborn Errors
 Heart Diseases Antibodies  >6 publications with GAMT and Heart Diseases
 Liver Diseases Antibodies  >6 publications with GAMT and Liver Diseases
 Muscular Diseases Antibodies  >5 publications with GAMT and Muscular Diseases
 Learning Disorders Antibodies  >5 publications with GAMT and Learning Disorders

Organs/Tissues associated with GAMT antibody pair kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >80 publications with GAMT and Brain
 Blood Antibodies  >57 publications with GAMT and Blood
 Liver Antibodies  >43 publications with GAMT and Liver
 Muscle Antibodies  >25 publications with GAMT and Muscle
 Heart Antibodies  >15 publications with GAMT and Heart
 Kidney Antibodies  >14 publications with GAMT and Kidney
 Pancreas Antibodies  >8 publications with GAMT and Pancreas
 Embryonic Tissue Antibodies  >5 publications with GAMT and Embryonic Tissue
 Testis Antibodies  >3 publications with GAMT and Testis
 Eye Antibodies  >3 publications with GAMT and Eye