Recombinant Mouse Claudin-18.2 (Cldn18.2)-VLPs (Active) - Mammalian cell
Référence CSB-MP005498MO(F3)-20ug
Conditionnement : 20ug
Marque : Cusabio
| Abbreviation | Recombinant Mouse Cldn18.2 protein-VLPs (Active) |
| MSDS | |
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Product Details
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Mouse Cldn18 at 5 μg/mL can bind Anti-CLDN18.2 recombinant antibody (CSB-RA005498A1HU), the EC50 is 6.115-11.01 ng/mL.
Target Names
Cldn18.2
Uniprot No.
Molecular Characterization
Species
Mus musculus (Mouse)
Source
Mammalian cell
Expression Region
1-264aa
Target Protein Sequence
MSVTACQGLGFVVSLIGFAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV
Mol. Weight
29.1 kDa
Protein Length
Full Length of Isoform A2.1
Tag Info
N-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions)
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
Claudin-18.2 has emerged as a high-priority therapeutic target in oncology due to its restricted expression pattern and tumor-specific accessibility, making functional protein reagents essential for antibody development campaigns. This recombinant mouse Cldn18.2 is presented as virus-like particles displaying the full-length protein (aa 1–264, Isoform A2.1), preserving native multi-pass transmembrane topology that conventional soluble constructs cannot achieve. Functional ELISA confirms robust binding to an anti-CLDN18.2 recombinant antibody with an EC50 of 6.115–11.01 ng/m...
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