Recombinant PoRV (strain TM-a) VP6 Protein

Référence DRA299-500ug

Conditionnement : 500ug

Marque : Novoprotein


Description
Recombinant PoRV(strain TM-a) VP6 Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys397 is expressed with a 6His tag at N-terminus.
Accession
AET79172.1
Known As
Intermediate capsid protein VP6; VP6 Protein; VP6
Mol Mass
46.8 kDa
APMol Mass
40-50 kDa, reducing conditions
Formulation Description
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Purity-SDS-PAGE
Greater than 90% as determined by reducing SDS-PAGE.
Storage
  • Reconstituted protein solution should be stored at ≤ -20°C.
  • Stable for at least 24 months when stored as instructed.
Shipping
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Background
Porcine rotavirus (PoRV) belongs to the genus Rotavirus in the family Reoviridae, and it is the most common viral causative agents of neonatal diarrhea in suckling and weaned piglets. Multiple serotypes of PoRV have been detected in diarrhea cases of suckling and weaning pigs. VP6 forms the intermediate layer of the rotavirus (RV) capsid, and it plays important roles after RV penetration and uncoating. VP4 and VP7 are responsible for the initial interactions of RV with host cells. VP6 is the most abundant PoRV structural protein, and it plays important roles after virus penetration and uncoating; thus, interactions between VP6 and viral/cellular proteins will involve in several major steps of RV infection after DLPs formation in the cytoplasm.