Sulfosuccinimidyl oleate sodium [1212012-37-7]

Biological Activity

Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect.

Product Citations

• 

  Cells. 2025 Mar 06;14(5):385.

  Selective Azapeptide CD36 Ligand MPE-298 Regulates oxLDL-LOX-1-Mediated Inflammation and Mitochondrial Oxidative Stress in Macrophages
  Sulfosuccinimidyl oleate sodium purchased from AbMole

Chemical Information

Molecular Weight	481.58
Formula	C22H36NNaO7S
CAS Number	1212012-37-7
Form	Solid
Solubility (25°C)	DMSO 60 mg/mL
Storage	2-8°C, dry, sealed

References

[1] Tomohito Mizuno, et al. J Biol Chem. Oxidized alkyl phospholipids stimulate sodium transport in proximal tubules via a nongenomic PPARγ-dependent pathway

[2] Hiramani Dhungana, et al. J Neuroinflammation. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation