Telmisartan-d3 [1189889-44-8]
Référence HY-13955S-10mg
Conditionnement : 10mg
Marque : MedChemExpress
Telmisartan-d3 is the deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM[1][2].
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Telmisartan-d3 Chemical Structure
CAS No. : 1189889-44-8
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Telmisartan-d3:
- Telmisartan In-stock
- Telmisartan-d7 In-stock
- Telmisartan-d4 Obtenir un devis
- Telmisartan-13C,d3 Obtenir un devis
Description |
Telmisartan-d3 is the deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM[1][2]. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Masse moléculaire |
517.64 |
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Formule |
C33H27D3N4O2 |
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CAS No. |
1189889-44-8 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
CC1=CC(C2=NC3=C(N2C([2H])([2H])[2H])C=CC=C3)=CC4=C1N=C(N4CC5=CC=C(C=C5)C6=CC=CC=C6C(O)=O)CCC |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
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Pureté et documentation | ||||||||||
Références |
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Telmisartan-d3 Related Classifications
Calculateur de molarité
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The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Telmisartan-d31189889-44-8Angiotensin ReceptorAutophagyInhibitorinhibitorinhibit