Conditionnement : 100ul
Antibodies made against full-length proteins as antigens.
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| Product Data | |
| Clone Name | OTI1C1 |
|---|---|
| Application | ELISA (indirect), FC, IF, WB |
| Recommended Dilution | WB 1:4000, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human TNF(NP_000585) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 25.5 kDa |
| Gene Name | tumor necrosis factor |
| Database Link | |
| Background | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. provided by RefSeq, Jul 2008 |
| Synonyms | DIF; TNF-alpha; TNFA; TNFSF2 |
| Reference Data | |
| Protein Categories | ADC Targets, Allergies and autoimmune diseases, Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane |
| Protein Pathways | Adipocytokine signaling pathway, Allograft rejection, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Asthma, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Fc epsilon RI signaling pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Natural killer cell mediated cytotoxicity, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus, Type II diabetes mellitus |
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| SDS |
| Antibody Resources |
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| SKU | Description | Size | ||
|---|---|---|---|---|
| CF506513 | Carrier-free (BSA/glycerol-free) TNF mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) | 100 ug | | |
| TA506513AM | TNF mouse monoclonal antibody,clone 1C1, Biotinylated | 100 ul | | |
| TA506513BM | TNF mouse monoclonal antibody,clone 1C1, HRP conjugated | 100 ul | | |
| TA506513S | TNF mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) | 30 ul | | |