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Uridine triphosphate trisodium salt [19817-92-6]

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Référence NB-64-44425-1mL

Conditionnement : 1mLx10mM(inH2O)

Marque : Neo Biotech

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Uridine triphosphate trisodium salt

(Synonyms: UTP, Trisodium Salt, Uridine triphosphate (trisodium salt), Uridine 5'-triphosphate trisodium salt) Copy Product Info

Synonyms: UTP, Trisodium Salt, Uridine triphosphate (trisodium salt), Uridine 5'-triphosphate trisodium salt

Catalog No. T8393 Copy Product Info

Purity: 99.83%

Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.

Cas No. 19817-92-6

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.83%

Appearance:solid

Color:White

Product Introduction

Uridine triphosphate trisodium salt AI Summary

Uridine triphosphate trisodium salt exhibits varying effects on cell viability, protein stability, and GPCR signaling pathways. In cell viability assays, the compound influences growth in HEK293T cells, U2OS cells, and human fibroblasts, with growth rates ranging from 0.09 to 0.99, showing both stimulatory and inhibitory effects on cell growth. In Thermal Shift Assays, Uridine triphosphate trisodium salt interacts with multiple domains of a protein, resulting in either stabilization or destabilization as indicated by changes in melting temperature (TM). The compound demonstrates diverse bioactivities in GPCR beta-arrestin recruitment assays across several targets, including ADGRF1, FFAR4, GPR35, ADRA2A, ADRB2, CX3CR1, GPR119, FPR2, S1PR1, GLP1R, APLNR, AGTR1, and C5AR1, exhibiting both agonistic and inhibitory effects. These findings suggest that Uridine triphosphate trisodium salt may act as a multi-target modulator with the potential to influence multiple biological pathways..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.
Synonyms	UTP, Trisodium Salt, Uridine triphosphate (trisodium salt), Uridine 5'-triphosphate trisodium salt

Chemical Properties

Molecular Weight	550.087
Formula	C₉H₁₂N₂Na₃O₁₅P₃
Cas No.	19817-92-6
Smiles	O[C@@H]([C@H]([C@H](N1C(NC(C=C1)=O)=O)O2)O)[C@H]2COP([O-])(OP([O-])(OP([O-])(O)=O)=O)=O.[Na+].[Na+].[Na+]
Relative Density.	2.106g/cm3

Storage & Solubility Information

Storage

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 50.00 mg/mL (90.89 mM), Sonication is recommended.

DMSO: 1.00 mg/mL (1.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.8179 mL	9.0895 mL	18.1789 mL	90.8947 mL

H2O

	1mg	5mg	10mg	50mg
5 mM	0.3636 mL	1.8179 mL	3.6358 mL	18.1789 mL
10 mM	0.1818 mL	0.9089 mL	1.8179 mL	9.0895 mL
20 mM	0.0909 mL	0.4545 mL	0.9089 mL	4.5447 mL
50 mM	0.0364 mL	0.1818 mL	0.3636 mL	1.8179 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

UTP trisodiumUridine triphosphate trisodium saltUridine triphosphate trisodiumUridine TriphosphateUridine 5'-triphosphate trisodiumUridine 5'-triphosphateUridineInhibitorinhibitEndogenous Metabolite

Related Tags: Uridine triphosphate trisodium salt chemical structure | Uridine triphosphate trisodium salt formula | Uridine triphosphate trisodium salt molecular weight