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> WRN Human Gene Knockout Kit (CRISPR)

WRN Human Gene Knockout Kit (CRISPR)

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Référence KN222919RB

Conditionnement : 1kit


WRN Human Gene Knockout Kit (CRISPR)

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SKU
KN222919RB
WRN - human gene knockout kit via CRISPR, HDR mediated
 

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Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol WRN
Locus ID 7486
Components

KN222919G1, WRN gRNA vector 1 in pCas-Guide CRISPR vector

KN222919G2, WRN gRNA vector 2 in pCas-Guide CRISPR vector

KN222919RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000553
UniProt ID Q14191
Synonyms RECQ3; RECQL2; RECQL3
Summary This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. provided by RefSeq, Aug 2017
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Product Manuals
FAQs
    FAQ for CRISPR Products
SDS
SKU Description Size
GA105162 WRN CRISPRa kit - CRISPR gene activation of human WRN RecQ like helicase 1 kit
KN222919 WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN222919BN WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN222919LP WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN422919 WRN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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