Ly49I Mouse Monoclonal Antibody [Clone ID: YLI-90]

Specifications

Product Data
Clone Name	YLI-90
Applications	FC
Recommended Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3)
Reactivities	Mouse
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Specificity	This antibody react with the B6 allele of the Ly49I. It stains ~ 45% of NK1.1+CD3- splenocytes from C57BL/6 mice. (Ref.1)
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Biotin
Storage	Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Database Link	UniProt ID Q9JHN9
Background	Ly49I is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.
Synonyms	Klra9, Ly-49I
Reference Data