Cd24a Rat Monoclonal Antibody [Clone ID: 91]

CAT#: AM08034AC-N

Cd24a rat monoclonal antibody, clone 91, APC

Conjugation: Unconjugated APC Biotin FITC PE


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Specifications

Product Data
Clone Name 91
Applications FC
Recommended Dilution Flow Cytometry: < / = 0.3 µg/10e6 cells. (Ref.8)
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).
Formulation PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
Label: APC
State: Liquid purified Ig fraction.
Label: Allophycocyanin
Concentration lot specific
Conjugation APC
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3).
The monoclonal antibody 91 can be used to inhibit B-cell differentiation. (Ref.8)
Synonyms X62 heat stable antigen, HSA
Reference Data

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