CD5 antibody [53-7.3] (APC-Cy7)
Référence GTX01465-15-100ug
Conditionnement : 100ug
Marque : Genetex
Host | Rat |
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Clonality | Monoclonal |
Clone Name | 53-7.3 |
Isotype | IgG2a |
Application | FACS |
Reactivity | Mouse |
Package | 100 μg |
View product citations for antibody GTX01465-15 on CiteAb
PRODUCT
Summary
The 53-7.3 monoclonal antibody is specific for mouse CD5, a 67 kDa protein that is expressed on most thymocytes, mature T cells and the B-1 subset of B cells. CD5 is a member of the scavenger receptor cysteine-rich protein superfamily and is a ligand for the c-type lectin CD72. CD5 is also known as Leu-1 and functions to modulate antigen receptor signaling on T and B cells.
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
FACS | Assay dependent |
Not tested in other applications.
Calculated MW
54 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Purification
Purified by affinity chromatography
From tissue culture supernatant
From tissue culture supernatant
Conjugation
Allophycocyanin-Cyanine7 (APC-Cy7)
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Cellular Localization
Cell membrane
Database
DATA IMAGES
GTX01465-15 FACS Image FACS analysis of mouse C57Bl/6 splenocytes using GTX01465-15 CD5 antibody [53-7.3] (APC-Cy7). |
Clone Reference
1998; CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.
1998; A role for CD5 in cognate interactions between T cells and B cells, and identification of a novel ligand for CD5.
1996; CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells.
1995; A role for CD5 in TCR-mediated signal transduction and thymocyte selection.
1983; The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.
Submit a Reference REVIEW
Clone Reference
1998; CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.
1998; A role for CD5 in cognate interactions between T cells and B cells, and identification of a novel ligand for CD5.
1996; CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells.
1995; A role for CD5 in TCR-mediated signal transduction and thymocyte selection.
1983; The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.
1980; T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.
SDS | |
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Sodium Azide.pdf |