General Info
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Cleaved-Complement C1r subcomponent-R463 (414-463 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | C1R |
| Gene ID: | 715 |
| Uniprot ID: | C1R_HUMAN |
| Immunogen Region: | 414-463 aa |
| Specificity: | Cleaved-C1r HC (R463) Polyclonal Antibody detects endogenous levels of fragment of activated C1r HC protein resulting from cleavage adjacent to R463. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human C1R at the amino acid range 414-463 |
Description
| Function | C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. |
| Protein Name | Complement C1r SubcomponentComplement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain |
| Database Links | Reactome: R-HSA-166663Reactome: R-HSA-173623Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement C1r Subcomponent antibodyAnti-Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain antibodyAnti-C1R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance