1-Naphthaleneacetic acid [86-87-3]
Référence HY-18570-5g
Conditionnement : 5g
Marque : MedChemExpress
1-Naphthaleneacetic acid (1-Naphthylacetic acid), a auxin, can promote plant growth. 1-Naphthaleneacetic acid is also an inhibitor of PLA2, with an IC50 of 13.16 μM.
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1-Naphthaleneacetic acid Chemical Structure
CAS No. : 86-87-3
Based on 1 publication(s) in Google Scholar
Other Forms of 1-Naphthaleneacetic acid:
- 1-Naphthaleneacetic acid potassium salt In-stock
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Description |
1-Naphthaleneacetic acid (1-Naphthylacetic acid), a auxin, can promote plant growth. 1-Naphthaleneacetic acid is also an inhibitor of PLA2, with an IC50 of 13.16 μM[1][2]. |
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IC50 & Target[1] |
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In Vitro |
1-Naphthaleneacetic acid (0.7-14 μM) inhibits the activity of PLA2, with the Ki and IC50 of 6.87 μM and 13.16 μM, respectively[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Masse moléculaire |
186.21 |
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Formule |
C12H10O2 |
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CAS No. |
86-87-3 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
OC(CC1=CC=CC2=C1C=CC=C2)=O |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
Store at room temperature |
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Solvant et solubilité |
In Vitro:
Methanol : 125 mg/mL (671.29 mM; Need ultrasonic) DMSO : ≥ 100 mg/mL (537.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) H2O : < 0.1 mg/mL (insoluble) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
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Pureté et documentation |
Purity: 99.89% |
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Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO / Methanol | 1 mM | 5.3703 mL | 26.8514 mL | 53.7028 mL | 134.2570 mL |
5 mM | 1.0741 mL | 5.3703 mL | 10.7406 mL | 26.8514 mL | |
10 mM | 0.5370 mL | 2.6851 mL | 5.3703 mL | 13.4257 mL | |
15 mM | 0.3580 mL | 1.7901 mL | 3.5802 mL | 8.9505 mL | |
20 mM | 0.2685 mL | 1.3426 mL | 2.6851 mL | 6.7129 mL | |
25 mM | 0.2148 mL | 1.0741 mL | 2.1481 mL | 5.3703 mL | |
30 mM | 0.1790 mL | 0.8950 mL | 1.7901 mL | 4.4752 mL | |
40 mM | 0.1343 mL | 0.6713 mL | 1.3426 mL | 3.3564 mL | |
50 mM | 0.1074 mL | 0.5370 mL | 1.0741 mL | 2.6851 mL | |
60 mM | 0.0895 mL | 0.4475 mL | 0.8950 mL | 2.2376 mL | |
80 mM | 0.0671 mL | 0.3356 mL | 0.6713 mL | 1.6782 mL | |
100 mM | 0.0537 mL | 0.2685 mL | 0.5370 mL | 1.3426 mL |
1-Naphthaleneacetic acid Related Classifications
- Others
- Metabolic Enzyme/Protease
- Phospholipase