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> 1-Oleoyl Lysophosphatidic Acid [65528-98-5]

1-Oleoyl Lysophosphatidic Acid [65528-98-5]

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Référence NB-64-24604-5mg

Conditionnement : 5mg

Marque : Neo Biotech


1-Oleoyl Lysophosphatidic Acid (Synonyms: Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA)

Catalog No. T36907 Copy Product Info
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.

1-Oleoyl Lysophosphatidic Acid

Copy Product Info
Synonyms Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA

1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.

1-Oleoyl Lysophosphatidic Acid
Cas No. 65528-98-5
Other Forms of 1-Oleoyl Lysophosphatidic Acid:
1-Oleoyl lysophosphatidic acid sodiumT21654325465-93-8
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Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Description
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.
In vivo
METHODS: 1-Oleoyl Lysophosphatidic Acid(0.4-2 μg, i.v. for 9 weeks) treated rats and behaviorally assessed.
RESULTS: 1-Oleoyl Lysophosphatidic Acid induced anxiety-like responses in the elevated plus maze (EPM). [5]
SynonymsOleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA
Chemical Properties
Molecular Weight436.52
FormulaC21H41O7P
Cas No.65528-98-5
SmilesO(C(CCCCCCC/C=C\CCCCCCCC)=O)C[C@H](COP(=O)(O)O)O
Relative Density.1.103 g/cm3 (Predicted)
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 10 mg/mL (22.91 mM), Sonication is recommended.
PBS (pH 7.2): 1 mg/mL (2.29 mM), Sonication is recommended.
DMF: 1 mg/mL (2.29 mM), Sonication is recommended.
DMSO: 1 mg/mL (2.29 mM), Sonication is recommended.
PBS (pH 7.2): 1 mg/mL (2.29 mM), Sonication is recommended.
Solution Preparation Table
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.