1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine [26853-31-6]
Référence sc-202396A
Conditionnement : 250mg
Marque : Santa Cruz Biotechnology
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (CAS 26853-31-6)
Application:
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine
Numéro CAS:
26853-31-6
Pureté:
≥98%
Masse Moléculaire:
760.10
Formule Moléculaire:
C42H82NO8P
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
* Consulter le Certificat d'Analyses pour les données spécifiques à un lot (incluant la teneur en eau).
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Description
Information Technique
Données de Sécurité
SDS & Certificat d’Analyses
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho), is a phosphatidylcholine, that belongs to a class of phospholipids that are a major component of biological membranes. This compound has been shown to decrease the expression of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit GluR1 on the plasma membrane of CA1 region of rat hippocampal slices. Experiments have reported that ozonation of POPhtCho produces 1-palmitoyl-2-[8-[3(5-octyl-1,2,4-trioxolan-3-yl)octanoyl]-sn-glycero-3- phosphocholine (PC-Criegee ozonide) and 1-palmitoyl-2-(9-oxononanoyl)-sn-glycero-3- phosphocholine (PC-aldehyde). Both PC-aldehyde and PC-Criegee ozonide have demonstrated the ability to alter the activity of PLA2 in phospholipid choline vesicles via modulation of membrane packing order.
References:
- Peptide binding to lipid bilayers. Nonclassical hydrophobic effect and membrane-induced pK shifts. | Beschiaschvili, G. and Seelig, J. 1992. Biochemistry. 31: 10044-53. PMID: 1390763
- Interaction of electric dipoles with phospholipid head groups. A 2H and 31P NMR study of phloretin and phloretin analogues in phosphatidylcholine membranes. | Bechinger, B. and Seelig, J. 1991. Biochemistry. 30: 3923-9. PMID: 1850293
- Reactions of dinitrogen pentoxide and nitrogen dioxide with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine. | Lai, CC. and Finlayson-Pitts, BJ. 1991. Lipids. 26: 306-14. PMID: 1865766
- 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine improves cognitive decline by enhancing long-term depression. | Yaguchi, T., et al. 2009. Behav Brain Res. 204: 129-32. PMID: 19482045
- A reconstitution method for integral membrane proteins in hybrid lipid-polymer vesicles for enhanced functional durability. | Seneviratne, R., et al. 2018. Methods. 147: 142-149. PMID: 29410153
- Highly shape- and size-tunable membrane nanopores made with DNA. | Xing, Y., et al. 2022. Nat Nanotechnol. 17: 708-713. PMID: 35484212
- Lipid solvation of cytochrome c oxidase. Deuterium, nitrogen-14, and phosphorus-31 nuclear magnetic resonance studies on the phosphocholine head group and on cis-unsaturated fatty acyl chains. | Tamm, LK. and Seelig, J. 1983. Biochemistry. 22: 1474-83. PMID: 6301550
- Activation of phospholipase A2 in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine liposomes containing lipid ozonation products. | Salgo, MG., et al. 1994. Chem Res Toxicol. 7: 458-62. PMID: 8075380
État Physique :
Solid
Solubilité :
Soluble in chloroform (20 mg/ml). Insoluble in water.
STOCKAGE :
Store at -20° C
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
WGK Allemagne :
3
PubChem CID :
5497103Numéro MDL :
MFCD00043212
Numéro CE :
248-056-7
Registre Beilstein :
4173237
SMILES :
CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC
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SAMPLE Certificate of Analysis (COA)
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | CAS 26853-31-6 SAMPLE Certificate of AnalysisCERTIFICAT D'ANALYSE
Numéro de catalogue
Numéro de Lot
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SAMPLE Certificate of Analysis (COA)
Catalog Number:sc-202396
Lot Number:SAMPLE
Product Name:1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
Molecular Formula:C42H82NO8P
Molecular Weight:760.1
Native Source:Synthetic
Test | Specification | Results |
---|---|---|
Appearance | Solid | |
Purity (TLC) | > 98% | |
Solubility | Methylene chloride and methanol |
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 50 mg | sc-202396 | 50 mg | .00 | |||
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 250 mg | sc-202396A | 250 mg | .00 | |||
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 500 mg | sc-202396B | 500 mg | .00 |