General Info
Host: | Mouse |
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-BPI is suitable for use in ELISA research applications. |
Clonality: | Monoclonal |
Clone ID: | 4H5 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | PBS with 0.1% BSA and 0.02% sodium azide |
Concentration: | 100 ug/mL |
Storage Instruction: | Store at 2-8°C upon receipt. |
Information
Description
Tissue Specificity | Restricted to cells of the myeloid series. |
Function | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |
Protein Name | Bactericidal Permeability-Increasing ProteinBpiCap 57 |
Database Links | Reactome: R-HSA-166016Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
Alternative Antibody Names | Anti-Bactericidal Permeability-Increasing Protein antibodyAnti-Bpi antibodyAnti-Cap 57 antibodyAnti-BPI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance