Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.

Anti-CASK Antibody FL490 Conjugate

Imprimer

Référence 75-000-FL490

Conditionnement : 200uL

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

Marque : Antibodies Incorporated

Demander plus d'informations

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

SKU: 75-000-FL490

Ships: 1-5 business days

Product Details

Target

CASK

Target Description

Calcium/Calmodulin-Dependent Serine Protein Kinase or CASK scaffolding protein is encoded by the gene CASK. CASK is a member of the MAGUK (membrane-associated guanylate kinase) protein family. CASK is a a calcium/calmodulin-dependent serine protein kinase. CASK is found in many different tissues including kidney, lung, liver and brain. In the brain, CASK protein is located at synapses. CASK acts as a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Mutations in this gene are associated with FG syndrome 4, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

K56A/50

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

CASK LIN2

Molecular Weight

100 kDa

Antigen

Fusion protein amino acids 318-415 of rat CASK/Lin2 (accession number Q62915) produced recombinantly in E. Coli

Species Reactivity

Chicken, Human, Mouse, Rat, Xenopus, Zebrafish

Antibody Registry ID

AB_2939060

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)

UniProt ID

O14936

Bulk Order Anti-CASK Antibody FL490 Conjugate

Vous serez peut-être également intéressé par les produits suivants :

Référence

Description

Cond.

Prix HT

24901-500

Picrosirius Red Stain Kit

500g

A2343-1ml

Cyclophosphamide [50-18-0]

10mM(in1mLDMSO)