General Info
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-GABRA3 (29-276) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | GABRA3 |
| Gene ID: | 2556 |
| Uniprot ID: | GBRA3_HUMAN |
| Immunogen Region: | 29-276 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-276 of human GABRA3 (NP_000799.1). |
| Immunogen Sequence: | QGESRRQEPGDFVKQDIGGL SPKHAPDIPDDSTDNITIFT RILDRLLDGYDNRLRPGLGD AVTEVKTDIYVTSFGPVSDT DMEYTIDVFFRQTWHDERLK FDGPMKILPLNNLLASKIWT PDTFFHNGKKSVAHNMTTPN KLLRLVDNGTLLYTMRLTIH AECPMHLEDFPMDVHACPLK FGSYAYTTAEVVYSWTLGKN KSVEVAQDGSRLNQYDLLGH VVGTEIIRSSTGEYVVMTT |
Description
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
| Protein Name | Gamma-Aminobutyric Acid Receptor Subunit Alpha-3Gaba(A Receptor Subunit Alpha-3 |
| Database Links | Reactome: R-HSA-977443 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Gamma-Aminobutyric Acid Receptor Subunit Alpha-3 antibodyAnti-Gaba(A Receptor Subunit Alpha-3 antibodyAnti-GABRA3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance