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> Anti-GPR55 Polyclonal Antibody

Anti-GPR55 Polyclonal Antibody

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Référence NB-64-156673-100uL

Conditionnement : 100uL

Marque : Neo Biotech


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Anti-GPR55 Polyclonal Antibody

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Synonyms:

Catalog No. TMAB-06724 Copy Product Info
Anti-GPR55 Polyclonal Antibody is a Rabbit antibody targeting GPR55. Anti-GPR55 Polyclonal Antibody can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Description
Anti-GPR55 Polyclonal Antibody is a Rabbit antibody targeting GPR55. Anti-GPR55 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse
Verified Activity
1. Sample:
Lane 1: Mouse Adrenal gland tissue lysates
Lane 2: Mouse Stomach tissue lysates
Primary: Anti-GPR55 (TMAB-06724) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
2. Sample: Embryo (Mouse) Lysate at 40 μg
Primary: Anti-GPR55 (TMAB-06724) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. Expressed in osteoclasts and osteoblasts.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundG protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR55 is a member of this family (subfamily Orphan-A). It has been reported to be expressed in the brain, where mRNA transcripts were detected in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain. ESTs have been isolated from liver/spleen libraries.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse CD69
Antigen Species
Mouse
Gene Name
GPR55
Gene ID
9290
Protein Name
G-protein coupled receptor 55
Function
May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function.
Chemical Properties
Molecular WeightTheoretical: 37 kDa. Actual: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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