General Info
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Leukotriene B4 receptor 1 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | LTB4R |
| Gene ID: | 1241 |
| Uniprot ID: | LT4R1_HUMAN |
| Specificity: | LT4R1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
Description
| Post Translational Modifications | Phosphorylated by GRK6 upon leukotriene B4 binding.which promotes desensitization. |
| Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
| Protein Name | Leukotriene B4 Receptor 1Ltb4-R 1Ltb4-R1Chemoattractant Receptor-Like 1G-Protein Coupled Receptor 16P2y Purinoceptor 7P2y7 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Leukotriene B4 Receptor 1 antibodyAnti-Ltb4-R 1 antibodyAnti-Ltb4-R1 antibodyAnti-Chemoattractant Receptor-Like 1 antibodyAnti-G-Protein Coupled Receptor 16 antibodyAnti-P2y Purinoceptor 7 antibodyAnti-P2y7 antibodyAnti-LTB4R antibodyAnti-BLT antibodyAnti-BLT1 antibodyAnti-BLTR antibodyAnti-CMKRL1 antibodyAnti-GPR16 antibodyAnti-P2RY7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance